Abstract
This chapter presents data supporting a possible role for cyclic nucleotides in neurotransmitter- and hormone-mediated events in invertebrates. Although a large number of studies are described, emphasis is placed on those preparations in which both physiological and biochemical data are available. Among the major topics treated are: (1) the effects of biogenic amines, calcium and cyclic nuleotides on secretory processes in insect salivary glands; (2) the “neuromodulatory” effects of serotonin and cyclic nucleotides in relatively long-term changes in synaptic efficacy, including heterosynaptic facilitation and behavioral sensitization; (3) the possible involvement of cyclic nucleotides in voltage-dependent amine responses; and (4) the role of cyclic AMP in mediating the neurogenic control of light emission in photogenic tissue. The above topics as well as others are organized and presented according to the hormone or transmitter mediating the various physiological processes. These hormones and transmitters include serotonin, octopamine, dopamine, and certain peptides.