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A MSLN targeted multifunctional nano-immunoliposome for MR imaging and targeting therapy in pancreatic cancer
Conference proceeding

A MSLN targeted multifunctional nano-immunoliposome for MR imaging and targeting therapy in pancreatic cancer

Li Deng, Xingfa Ke, Zhiying He and Jianming Chen
2012年中国药物制剂大会——中国药学会药剂专业委员会年会、亚洲阿登制药技术研讨会暨国际控释协会中国分会年会
09/19/2012

Abstract

nanoimmunoliposome theranostic nanomedicine Mesothelin doxorubicin USPIO Pancreatic Cancer
Organizer: 中国药学会;   Aim:To provide a novel early diagnostic method and targeted therapy for pancreatic cancer.Methods:a multifunctional nano-immunoliposome with high loading of ultrasmall superparamagnetic iron oxides (USPIOs) and doxorubicin (DOX) was prepared by transient binding and reverse phase evaporation(REV) method,and was conjugated with anti-mesothelin(MSLN) antibody by post insertion method to target mesothelin over expressed pancreatic cancer cells.

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