Abstract
Neu5Acα-(2-6)-Galβ-(1-4)-GlcNAc trisaccharide has been shown to be a known sialic acid glycan linkage. The synthesis towards Neu5Acα-(2-6)-Galβ-(1-4)-GlcNAc trisaccharide involved using acetylation, deacetylation, benzylidenation, debenzylidenation, Koenigs-Knor glycosylation, Schmidt glycosylation, and sialylation reactions. The Galβ-(1-4)-GlcNAc disaccharide was successfully synthesized and will be employed in the studies towards the synthesis of Neu5Acα-(2-6)-Galβ-(1-4)-GlcNAc trisaccharide.