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A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks
Journal article   Open access   Peer reviewed

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

Oren Parnas, Marko Jovanovic, Thomas M Eisenhaure, Rebecca H Herbst, Atray Dixit, Chun Jimmie Ye, Dariusz Przybylski, Randall J Platt, Itay Tirosh, Neville E Sanjana, …
Cell, Vol.162(3), pp.675-686
07/30/2015
PMCID: PMC4522370
PMID: 26189680

Abstract

Cell Survival Dendritic Cells - immunology Mice, Transgenic Hexosyltransferases - metabolism Toll-Like Receptor 4 - immunology Gene Knockout Techniques Gene Regulatory Networks Genetic Techniques Immunity, Innate Animals Bone Marrow Cells - immunology CRISPR-Cas Systems Tumor Necrosis Factor-alpha - immunology Dendritic Cells - cytology Membrane Proteins - metabolism Mice Cell Differentiation
url
https://doi.org/10.1016/j.cell.2015.06.059View
Published (Version of record) Open

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