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Antibody recognition of HIV and dengue glycoproteins
Journal article   Open access   Peer reviewed

Antibody recognition of HIV and dengue glycoproteins

Isaac J Krauss
Glycobiology (Oxford), Vol.26(8), pp.813-819
08/2016
PMCID: PMC5018046
PMID: 26941393

Abstract

Antibodies, Viral - metabolism Epitopes - metabolism Humans Antibodies, Neutralizing - metabolism HIV Envelope Protein gp120 - metabolism Epitopes - immunology HIV Envelope Protein gp120 - immunology HIV Infections - immunology Antibodies, Neutralizing - immunology Dengue Virus - immunology HIV-1 - chemistry Viral Envelope Proteins - metabolism Protein Interaction Domains and Motifs HIV Envelope Protein gp120 - chemistry Dengue - immunology Binding Sites Protein Conformation, alpha-Helical HIV Infections - virology Models, Molecular Dengue - virology Dengue Virus - chemistry HIV-1 - immunology Protein Conformation, beta-Strand Antibodies, Neutralizing - chemistry Viral Envelope Proteins - chemistry Antibodies, Viral - chemistry Protein Binding Antibodies, Viral - immunology Viral Envelope Proteins - immunology Epitopes - chemistry Biochemistry Human Immunodeficiency Virus--HIV Immunology
The last 6 years have witnessed an explosion of discoveries at the interface of glycobiology and immunology. Binding of clustered oligosaccharides has turned out to be a very frequent mode by which human antibodies have developed broadly neutralizing activity against HIV. This mini-review will cover many recent developments in the HIV antibody field, as well as emerging data about Dengue broadly neutralizing antibodies.

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

#3 Good Health and Well-Being
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