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Conservation of cytoplasmic poly (A)-containing RNA in mouse and rat
Journal article   Peer reviewed

Conservation of cytoplasmic poly (A)-containing RNA in mouse and rat

M Rosbash, M S Campo and K S Gummerson
Nature (London), Vol.258(5537), pp.682-686
12/25/1975
DOI: https://doi.org/10.1038/258682a0
PMID: 1207748

Abstract

Nucleic Acid Hybridization Genetic Code Rats Templates, Genetic Cytoplasm - metabolism DNA - metabolism Hot Temperature RNA, Messenger - metabolism Biological Evolution Poly A - metabolism Animals Alleles Transcription, Genetic Mice
By comparing the melting temperature of DNA-DNA duplexes between related species, it is shown that total single-copy DNA evolves at a faster rate that DNA which is transcribed into poly (A)-containing RNA. Such a comparison suggests that at least 70% of rat single-copy DNA does not code for protein.

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