Converting trypsin to chymotrypsin : the role of surface loops

Journal article

Peer reviewed

Converting trypsin to chymotrypsin : the role of surface loops

L HEDSTROM, L SZILAGYI and W. J RUTTER

Science (American Association for the Advancement of Science), Vol.255(5049), pp.1249-1253

1992

DOI: https://doi.org/10.1126/science.1546324

PMID: 1546324

Abstract

Fundamental and applied biological sciences. Psychology

Biological and medical sciences

Hydrolases

Analytical, structural and metabolic biochemistry

Enzymes and enzyme inhibitors

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Title: Converting trypsin to chymotrypsin : the role of surface loops
Creators: L HEDSTROM - Univ. California, hormone res. inst., dep. biochemistry biophysics, San Francisco CA 94143-0534, United States
L SZILAGYI - Univ. California, hormone res. inst., dep. biochemistry biophysics, San Francisco CA 94143-0534, United States
W. J RUTTER - Univ. California, hormone res. inst., dep. biochemistry biophysics, San Francisco CA 94143-0534, United States
Publication Details: Science (American Association for the Advancement of Science), Vol.255(5049), pp.1249-1253
Publisher: American Association for the Advancement of Science; Washington, DC
Identifiers: 9923972923901921
Academic Unit: Department of Biology; Department of Chemistry
Language: English
Resource Type: Journal article