Logo image
Home Academic units
Sign in
Dephosphorylation of the Atg1 kinase complex by type 2C protein phosphatases
Journal article   Open access

Dephosphorylation of the Atg1 kinase complex by type 2C protein phosphatases

Gonen Memisoglu and James E Haber
Molecular & cellular oncology, Vol.6(3), pp.1588658-1588658
04/08/2019
PMCID: PMC6512942
PMID: 31131308

Abstract

Atg1 phosphatase autophagy PP2C Atg13
In budding yeast, Atg1 kinase, together with Atg13 and Atg17, forms a complex that is essential for autophagy. Previous work showed that the Atg1 kinase complex is regulated extensively by phosphorylations. Our recent paper demonstrates that type 2C protein phosphatases Ptc2 and Ptc3 are involved in the dephosphorylation of Atg13 and Atg1 kinase to promote autophagy.
pdf
Dephosphorylation of the Atg1 kinase complex by type 2C protein phosphatases815.17 kBDownloadView
Open Access
url
https://doi.org/10.1080/23723556.2019.1588658View
Published (Version of record) Open

Metrics

9 File views/ downloads
33 Record Views

Details