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Efficient one-pot syntheses of α- d-arabinofuranosyl tri- and tetrasaccharides present in cell wall polysaccharide of Mycobacterium tuberculosis
Journal article   Peer reviewed

Efficient one-pot syntheses of α- d-arabinofuranosyl tri- and tetrasaccharides present in cell wall polysaccharide of Mycobacterium tuberculosis

Xing-Yong Liang, Li-Min Deng, Xia Liu and Jin-Song Yang
Tetrahedron, Vol.66(1), pp.87-93
01/02/2010

Abstract

One-pot glycosylation Chemoselective glycosylation Mycobacterium tuberculosis Arabinofuranose
Two α-d-arabinofuranosyl oligosaccharides (2 and 3) found as constituent parts of the polysaccharide portion from the cell wall of Mycobacterium tuberculosis have been efficiently synthesized via a one-pot glycosylation procedure in which a key step is the chemoselective activation between d-arabinofuranosyl trichloroacetimidate donor 4 and partially protected aryl thioglycosides 5 or 7, respectively.

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