Oxidative free-radical annulation of dichloroacetophenone (7) with terminal alkenes provides modest to good yields of 4-substituted 2,2-dichloro-l-tetralones (10). The synthetic utility and reactivity of 10a is described.
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Title
Formation of 2,2-Dichloro-1-Tetralones by Oxidative Free-Radical Annulation
Creators
Barry B Snider -
Department of Chemistry , Brandeis University
Luning Han -
Department of Chemistry , Brandeis University