Formation of seven- and eight-membered rings by manganese (III)-based oxidative free radical cyclization

John E Merritt; Marvin Sasson; Steven A Kates; Barry B Snider

doi:10.1016/S0040-4039(00)80718-2

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Formation of seven- and eight-membered rings by manganese (III)-based oxidative free radical cyclization

Journal article

Peer reviewed

Formation of seven- and eight-membered rings by manganese (III)-based oxidative free radical cyclization

John E Merritt, Marvin Sasson, Steven A Kates and Barry B Snider

Tetrahedron letters, Vol.29(41), pp.5209-5212

1988

DOI: https://doi.org/10.1016/S0040-4039(00)80718-2

Abstract

Oxidation

Cyclization

Free radicals

Esters

Alicyclic compounds

Chemical Reactions

Organic Chemistry

Oxidative free radical cyclizations of β-ketoesters 1, 5, 11, and 14 with Mn(OAc)3·2H2O and Cu(OAc)2·H2O proceed in moderate yield to give seven- and eight-membered rings. The regiochemistry of the cyclization and oxidative termination are described.

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Title: Formation of seven- and eight-membered rings by manganese (III)-based oxidative free radical cyclization
Creators: John E Merritt (Author)
Marvin Sasson (Author)
Steven A Kates (Author)
Barry B Snider (Author)
Publication Details: Tetrahedron letters, Vol.29(41), pp.5209-5212
Publisher: Elsevier Ltd
Identifiers: 9924012821001921
Academic Unit: Department of Chemistry
Language: English
Resource Type: Journal article

Formation of seven- and eight-membered rings by manganese (III)-based oxidative free radical cyclization

Abstract

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