Abstract
Treatment of 2,4-dimethoxybenzyl alcohol with trifluoroacetic acid (TFA, 5% in CHCl3) affords, in almost quantitative yield calix[4]resorcinarene octamethyl ether, which on demethylation and acetylation yields the derived octa-acetate.
Treatment of 2,4-dimethoxybenzyl alcohol with TFA affords, in almost quantitative yield, calix[4]resorcinarene octamethyl ether 3, which on demethylation and acetylation yields the derived octa-acetate 6.