Hydroxylation Regiochemistry Is Robust to Active Site Mutations in Cytochrome P450

Journal article

Peer reviewed

Hydroxylation Regiochemistry Is Robust to Active Site Mutations in Cytochrome P450

Guadalupe Alvarez, Thu Le, Nathan Wong, Julian Echave, Thomas C Pochapsky and Eliana K Asciutto

Biochemistry (Easton), Vol.61(17)

08/06/2023

DOI: https://doi.org/10.1021/acs.biochem.2c00233

PMCID: PMC9721313

PMID: 35960510

Abstract

Oxygen

Catalytic Domain

Hydroxylation

Camphor

Camphor 5-Monooxygenase

Substrate Specificity

Cytochrome P-450 Enzyme System

Mutation

Cytochrome P450

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Details

Title: Hydroxylation Regiochemistry Is Robust to Active Site Mutations in Cytochrome P450
Creators: Guadalupe Alvarez
Thu Le
Nathan Wong
Julian Echave
Thomas C Pochapsky
Eliana K Asciutto
Publication Details: Biochemistry (Easton), Vol.61(17)
Identifiers: 9924316878901921
Academic Unit: Rosenstiel Basic Medical Sciences Research Center; Department of Chemistry
Language: English
Resource Type: Journal article