IMP dehydrogenase: structure, mechanism, and inhibition

Journal article

Open access

Peer reviewed

Chemical Reviews, Vol.109(7), pp.2903-2928

07/08/2009

PMCID: PMC2737513

PMID: 19480389

Abstract

Protein Structure, Tertiary

IMP Dehydrogenase - metabolism

Catalytic Domain

IMP Dehydrogenase - antagonists & inhibitors

IMP Dehydrogenase - chemistry

Enzyme Inhibitors - chemistry

Humans

Enzyme Inhibitors - pharmacology

Neoplasms - enzymology

Substrate Specificity

Kinetics

url

https://doi.org/10.1021/cr900021wView

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Title: IMP dehydrogenase: structure, mechanism, and inhibition
Creators: Lizbeth Hedstrom - Department of Biology, Brandeis University, MS009, 415 South Street, Waltham, Massachusetts 02454, USA. hedstrom@brandeis.edu
Publication Details: Chemical Reviews, Vol.109(7), pp.2903-2928
Publisher: United States
Grant note: GM54403 / NIGMS NIH HHS P41 RR-01081 / NCRR NIH HHS P41 RR001081 / NCRR NIH HHS R01 GM054403 / NIGMS NIH HHS R01 GM054403-10 / NIGMS NIH HHS
Identifiers: 9923958171401921
Academic Unit: Department of Chemistry; Department of Biology
Language: English
Resource Type: Journal article