Abstract
This review treats almost exclusively of investigations that have been published over
the last three years (for work prior to that period see I). Preference is given to data
obtained from identified neurons, in particular, from neurons for which the transmitter has been evaluated biochemically as well as electrophysiologically and pharmacologically. Finally, only those synaptic studies that deal directly with the
problems of transmitter pharmacology have been considered.
The first half of this review deals with recent advances in single-cell neurochemistry. Biochemical and histochemical work concerned with the identification of transmitters in identified neurons is summarized in Table 1, and is followed by a brief
consideration of some issues raised by the table and by other recent work in this field.
The second half of this review covers electro physiological and pharmacological
studies that clarify the role of transmitters or putative transmitters at some identified
junctions, giving preferential treatment to experimental preparations and problems
that have received rather extensive attention.