Abstract
Histone H1° is an HI subfraction whose level on the chromatin is inversely correlated with the mitotic index of the cell. We investigated the increase in H1° in 6 cell lines when cell division was blocked by 4 methods: 5 mM butyrate, 2% DMSO, serum withdrawal or density inhibition. The 6 cell lines (HeLa S1 and S3, CHO, 3T6, NIE-115 and Vero) responded differently to the treatments as regards the amount of increase in Hl° and comparisons among the lines reveal no obvious similarities between the lines in the differential effects of the various treatments on H1° levels.
Histone H1°
Cell culture
Butyrate
DMSO
Serum withdrawal
Density inhibition