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Maintaining your youthful spontaneity: Microcircuit homeostasis in the embryonic spinal cord
Journal article   Open access   Peer reviewed

Maintaining your youthful spontaneity: Microcircuit homeostasis in the embryonic spinal cord

Gina G. Turrigiano
Neuron (Cambridge, Mass.), Vol.49(4), pp.481-483
02/16/2006
DOI: https://doi.org/10.1016/j.neuron.2006.01.029
PMID: 16476657

Abstract

Nerve Net - embryology Spinal Cord - embryology Motor Neurons - physiology Synapses - physiology Homeostasis - physiology Spinal Cord - physiology Spinal Cord - cytology Chick Embryo Nerve Net - physiology SNA Developmental Neurobiology Neurobiology Neurogenesis Plasticity
Many developing networks generate spontaneous network activity (SNA) that plays an important role in setting up functional circuitry, but how the proper level and pattern of SNA is itself maintained has not been clear. In this issue of Neuron, Gonzalez-Islas and Wenner show that SNA in the intact embryo regulates itself through a set of adaptive homeostatic plasticity mechanisms.
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https://doi.org/10.1016/j.neuron.2006.01.029View
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