Abstract
On the anniversary of the Boyden etal. (2005) paper that introduced the use of channelrhodopsin in neurons, Nature Neuroscience asks selected members of the community to comment on the utility, impact and future of this important technique.
- Title
- Optogenetics: 10 years after ChR2 in neurons
- Creators
- Antoine Adamantidis - Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montréal, Canada, and the Department of Neurology, Inselspital University Hospital, University of Bern, Bern, SwitzerlandSilvia Arber - Biozentrum, Department of Cell Biology, University of Basel, Basel, Switzerland, and the Friedrich Miescher Institute for Biomedical Research, Basel, SwitzerlandJaideep S Bains - Department of Physiology and Pharmacology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, CanadaErnst Bamberg - Max Planck Institute of Biophysics, Frankfurt am Main, GermanyAntonello Bonci - Intramural Research Program, Synaptic Plasticity Section, National Institute on Drug Abuse, Baltimore, Maryland, USA, the Solomon H. Snyder Neuroscience Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA, and in the Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USAGyörgy Buzsáki - The Neuroscience Institute, School of Medicine and Center for Neural Science, New York University, New York, New York, USAJessica A Cardin - Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, USA, and at the Kavli Institute of Neuroscience, Yale University, New Haven, Connecticut, USARui M Costa - Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Lisbon, PortugalYang Dan - Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, California, USAYukiko Goda - RIKEN Brain Science Institute, Wako-shi, Saitama, JapanAnn M Graybiel - McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USAMichael Häusser - Wolfson Institute for Biomedical Research and Department of Neuroscience, Physiology and Pharmacology, University College London, London, United KingdomPeter Hegemann - Institut für Biologie/Experimentelle Biophysik, Humboldt Universität zu Berlin, Berlin, GermanyJohn R Huguenard - Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USAThomas R Insel - National Institute of Mental Health, Bethesda, Maryland, USAPatricia H Janak - Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland, USA, and the Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland, USADaniel Johnston - Department of Neuroscience and Center for Learning and Memory, University of Texas at Austin, Austin, Texas, USASheena A Josselyn - Program in Neurosciences and Mental Health, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada, and the Departments of Psychology and Physiology and Institute of Medical Science, University of Toronto, Toronto, Ontario, CanadaChristof Koch - Allen Institute for Brain Science, Seattle, Washington, USAAnatol C Kreitzer - The Gladstone Institutes, San Francisco, California, USA, and the Departments of Neurology and Physiology, University of California, San Francisco, San Francisco, California, USAChristian Lüscher - Department of Basic Neurosciences, University of Geneva, Geneva, Switzerland, and the Service of Neurology, Department of Clinical Neurosciences, University Hospital of Geneva, Geneva, SwitzerlandRobert C Malenka - Nancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, California, USAGero Miesenböck - Centre for Neural Circuits and Behaviour, University of Oxford, Tinsley Building, Mansfield Road, Oxford, UKGeorg Nagel - Institute for Molecular Plant Physiology and Biophysics, Biocenter, Julius-Maximilians-University of Würzburg, Würzburg, GermanyBotond Roska - Neural Circuit Laboratories, Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland. Department of Ophthalmology, University of Basel, Basel, SwitzerlandMark J Schnitzer - James H. Clark Center for Biomedical Engineering and Sciences, Stanford University, Stanford, California, USA, the Howard Hughes Medical Institute, Stanford University, Stanford, California, USA, and the CNC Program, Stanford University, Stanford, California, USAKrishna V Shenoy - Departments of Electrical Engineering, Bioengineering and Neurobiology, the Neurosciences and Bio-X Programs, the Stanford Neurosciences Institute and the Howard Hughes Medical Institute, Stanford University, Stanford, California, USAIvan Soltesz - Department of Neurosurgery, Stanford University, Stanford, California, USAScott M Sternson - Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USARichard W Tsien - Department of Neuroscience and Physiology, Neuroscience Institute, New York University Langone Medical Center, New York, New York, USAGina G. Turrigiano - Brandeis University, Department of BiologyKay M Tye - The Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts, USARachel I Wilson - Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA
- Publication Details
- Nature neuroscience, Vol.18(9), pp.1202-1212
- Publisher
- Nature Publishing Group; United States
- Grant note
- 084655 / Wellcome Trust 094077 / Wellcome Trust R01 NS027177 / NINDS NIH HHS 090309 / Wellcome Trust R01 NS090911 / NINDS NIH HHS R01 NS034774 / NINDS NIH HHS
- Identifiers
- 9923906568801921
- Copyright
- 2015 Nature Publishing Group
- Academic Unit
- Department of Biology; Benjamin and Mae Volen National Center for Complex Systems
- Language
- English
- Resource Type
- Journal article