Logo image
 Home Academic units
Sign in
Back
Ortho-hydroxylation of benzoic acids with hydrogen peroxide at a non-heme iron center
Journal article

Ortho-hydroxylation of benzoic acids with hydrogen peroxide at a non-heme iron center

Sonia Taktak, Margaret Flook, Bruce M Foxman, Lawrence Que, Jr and Elena V Rybak-Akimova
Chemical communications (Cambridge, England), (42), pp.5301-5303
11/14/2005
DOI: https://doi.org/10.1039/b508004e
PMID: 16244735

Abstract

Hydrogen Peroxide - chemistry Models, Molecular Molecular Structure Hydroxylation Nonheme Iron Proteins - chemistry Benzoates - chemistry
The iron-assisted hydroxylation of benzoic acid to salicylic acid by 1/H2O2 has been achieved in good yield under mild conditions (where is [Fe(II)(BPMEN)(CH3CN)2](ClO4)2 and BPMEN =N,N'-dimethyl-N,N'-bis(2-pyridylmethyl)ethane-1,2-diamine); the product of this reaction is a novel mononuclear iron(III) complex with a chelating salicylate.

Metrics

124 Record Views

Details