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Reduction of conductance-based neuron models
Journal article   Peer reviewed

Reduction of conductance-based neuron models

Thomas B Kepler, L. F Abbott and Eve Marder
Biological cybernetics, Vol.66(5), pp.381-387
03/1992
PMID: 1562643

Abstract

Differential Equation Original System Neuron Model Realistic Neuron Realistic Neuron Model
We present a scheme for systematically reducing the number of differential equations required for biophysically realistic neuron models. The techniques are general, are designed to be applicable to a large set of such models and retain in the reduced system as high a degree of fidelity to the original system as possible. As examples, we provide reductions of the Hodgkin-Huxley system and the A-current model of Connor et al. (1977).

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