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Syntheses Of (±)-Raikovenal, (±)-Preraikovenal, and (±)-Epiraikovenal
Journal article   Peer reviewed

Syntheses Of (±)-Raikovenal, (±)-Preraikovenal, and (±)-Epiraikovenal

Barry B Snider and Qing Lu
Synthetic communications, Vol.27(9), pp.1583-1600
05/01/1997

Abstract

(±)-Raikovenal (1a) has been synthesized in five steps from dihydrofilifolone (3) by two Wittig reactions. A similar sequence provides (±)-preraikovenal from aldehyde 11. Epiraikovenal (1b) has been prepared by photolysis of preraikovenal or by photolysis of 5 to give 4b. Lewis acid induced cyclization of enal 5 gives cyclopentylideneacetaldehyde 16 rather than bicyclo[3.2.0]heptanecarboxaldehyde 4.

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