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Synthesis of (±)-7-Hydroxylycopodine
Journal article   Open access   Peer reviewed

Synthesis of (±)-7-Hydroxylycopodine

Hong-Yu Lin and Barry B Snider
Organic letters, Vol.13(5), pp.1234-1237
03/04/2011
DOI: https://doi.org/10.1021/ol200119h
PMCID: PMC3056437
PMID: 21271726

Abstract

A six step synthesis of (±)-7-hydroxylycopodine has been achieved in 5% overall yield. In the key step, a Prins cyclization of a bicyclic keto alkyne in 60% H2SO4 forms a tricyclic dihydroxy amino ketone.
url
https://doi.org/10.1021/ol200119hView
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