Abstract
Deoxytabtoxinine-β-lactam (12) was synthesized in 6 steps from 3. β-Lactam 12 does not inhibit glutamine synthetase indicating that the hydroxyl group of tabtoxinine-β-lactam (2) is necessary for inhibition of glutamine synthetase.
- Title
- Synthesis of Deoxytabtoxinine-β-Lactam
- Creators
- Barry B Snider (Author) - Department of Chemistry , Brandeis UniversityMadeline I Johnston (Author) - Department of Chemistry , Brandeis University
- Publication Details
- Synthetic communications, Vol.17(16), pp.1877-1886
- Publisher
- Taylor & Francis Group
- Identifiers
- 9924012822101921
- Copyright
- © 1987 Taylor & Francis
- Academic Unit
- Department of Chemistry
- Language
- English
- Resource Type
- Journal article