Logo image
 Home Academic units
Sign in
Back
Synthesis of the N-((1E)-Alkenyl)-(2Z,4Z)-heptadienamide Side Chain of Salicylihalamide A and Apicularens A and B
Journal article   Peer reviewed

Synthesis of the N-((1E)-Alkenyl)-(2Z,4Z)-heptadienamide Side Chain of Salicylihalamide A and Apicularens A and B

Barry B Snider and Fengbin Song
Organic letters, Vol.2(3), pp.407-408
02/10/2000
DOI: https://doi.org/10.1021/ol991388+
PMID: 10814335

Abstract

Anions Hydrocarbons Silica Silver Biochemistry Chemical Synthesis Chromatography
The unstable N-((1E)-alkenyl)-(2Z,4Z)-heptadienamide side chain of salicylihalamide A (1) and apicularens A and B (3 and 4) has been prepared in one pot by the addition of (1Z,3Z)-hexadienylcuprate, prepared in situ from EtLi, CuBr·SMe2, and acetylene, to a (1E)-alkenyl isocyanate.

Metrics

34 Record Views

Details