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Synthesis of the hexahydronaphthalene moiety of (+)-mevinolin
Journal article   Peer reviewed

Synthesis of the hexahydronaphthalene moiety of (+)-mevinolin

Ethan A Deutsch and Barry B Snider
Tetrahedron letters, Vol.24(35), pp.3701-3704
1983

Abstract

The synthesis of the hexahydronaphthalene moiety () of (+)-mevinolin () has been achieved in 10 steps using an intramolecular Diels-Alder reaction of an alkenylallene to set up four of the chiral centers and the diene unit of ().

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