Abstract
Condensation of pyridone 6 with enal 25 using DMAP in EtOH at 150°C afforded 8% of the desired Diels-Alder adduct 22, 8% of the bridged adduct 36 and 1-2% of a partially pure cis-fused adduct 37 of unknown stereochemistry. Hydroxylation of 22 completed a short synthesis of fusaricide (1).