Abstract
Temperature experience-regulated gene expression changes have been shown to underlie long-term adaptation of the response threshold of the AFD thermosensory neuron pair, and contribute to thermotaxis behavioral plasticity in
C. elegans
. We previously showed that the
SRTX-1
GPCR is expressed primarily in AFD and is localized to their sensory endings. Here we find that
SRTX-1
levels are regulated by the animal's temperature experience. However, loss or overexpression of
srtx-1
does not affect thermotaxis behaviors or examined temperature-evoked calcium responses in AFD. Our observations suggest that
SRTX-1
may modulate AFD responses and behavior under defined temperature conditions, or in response to specific environmental stimuli.