Abstract
The sharing and reuse of clinical and biomedical data have been increasing with transformational results for health care. Therapies for coronavirus disease were generated in record time during the pandemic as a result of data sharing and reuse, for example. Yet, progress on breast cancer, dementia, infant mortality, and countless other diseases and outcomes is now at risk due to recent interruptions in data collection, loss of funding for data repositories, and cuts in the basic science that generates new data. Although some losses appear to be irreparable, collective action taken quickly by multistakeholder consortia will offer pathways to mitigate some of the worst harms.