Abstract
An iron‐mediated one‐pot synthesis of 3‐arylquinolines from o‐nitrobenzaldehydes and β‐nitrostyrenes has been developed. Iron acted as dual roles to trigger the reduction of o‐nitrobenzaldehydes and reduction hydrolysis of β‐nitrostyrenes, which subsequently integrated to quinoline derivatives.
A novel and efficient protocol for the synthesis of 3‐arylquinolines from o‐nitrobenzaldehydes and β‐nitrostyrenes promoted by iron has been developed. Iron acted as a double‐reducing reagent to trigger the reduction of o‐nitrobenzaldehydes and reduction hydrolysis of β‐nitrostyrenes to generate phenylaldehydes and o‐aminobenzaldehydes, which subsequently integrated to quinoline derivatives.
