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The Touching Tail of a Mechanotransduction Channel
Journal article   Open access   Peer reviewed

The Touching Tail of a Mechanotransduction Channel

Zachary A Knecht, Rachelle Gaudet and Paul A Garrity
Cell (Cambridge), Vol.162(6), pp.1214-1216
09/10/2015
PMID: 26359983

Abstract

Mechanotransduction, Cellular Animals Transient Receptor Potential Channels - chemistry Drosophila - metabolism Drosophila Proteins - chemistry Transient Receptor Potential Channels - metabolism Drosophila Proteins - metabolism
In mechanotransduction, sensory receptors convert force into electrical signals to mediate such diverse functions as touch, pain, and hearing. In this issue of Cell, Zhang et al. present evidence that the fly NompC channel senses mechanical stimuli using its N-terminal tail as a tether between the cell membrane and microtubules.
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https://doi.org/10.1016/j.cell.2015.08.049View
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