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The oxidation of aldehydes to acids with calcium hypochlorite [Ca(OCl) 2]
Journal article   Peer reviewed

The oxidation of aldehydes to acids with calcium hypochlorite [Ca(OCl) 2]

Stephen O Nwaukwa and Philip M Keehn
Tetrahedron letters, Vol.23(31), pp.3131-3134
1982

Abstract

Calcium hypochlorite is an efficient reagent for the oxidation of aldehydes to the corresponding acids. Reactions are carried out at ambient temperature in aqueous acetonitrile-acetic acid solution. Aliphatic aldehydes and aromatic aldehydes with electron withdrawing groups afford good to excellent yields. Nuclear chlorination is the preferred reaction in aromatic aldehydes with electron donating groups.

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