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Total synthesis of floresolide B and Delta(6,7)-Z-floresolide B
Journal article

Total synthesis of floresolide B and Delta(6,7)-Z-floresolide B

K C Nicolaou and Hao Xu
Chemical communications (Cambridge, England), (6), pp.600-602
02/14/2006
PMID: 16446822

Abstract

Alkenes - chemistry Biological Products - chemical synthesis Models, Chemical Antineoplastic Agents - chemical synthesis Marine Toxins - chemical synthesis Isomerism Macrocyclic Compounds - chemical synthesis
The total syntheses of the cytotoxin marine natural product floresolide B (1) and its Delta(6,7)-Z isomer (2) have been achieved through an olefin metathesis-based strategy.

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