Alkenes - chemistry Biological Products - chemical synthesis Models, Chemical Antineoplastic Agents - chemical synthesis Marine Toxins - chemical synthesis Isomerism Macrocyclic Compounds - chemical synthesis
The total syntheses of the cytotoxin marine natural product floresolide B (1) and its Delta(6,7)-Z isomer (2) have been achieved through an olefin metathesis-based strategy.
Total synthesis of floresolide B and Delta(6,7)-Z-floresolide B
Creators
K C Nicolaou -
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. kcn@scripps.edu
Hao Xu
Publication Details
Chemical communications (Cambridge, England), (6), pp.600-602