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Unexpected Formation of Hexasubstituted Arenes through a 2-fold Palladium-Mediated Ligand Arylation
Journal article   Peer reviewed

Unexpected Formation of Hexasubstituted Arenes through a 2-fold Palladium-Mediated Ligand Arylation

Corin C Wagen, Bryan T Ingoglia and Stephen L Buchwald
Journal of organic chemistry, Vol.84(19), pp.12672-12679
10/04/2019
PMID: 31512875

Abstract

Color Hydrocarbons Mixtures Biopolymers Aromatic Compounds
A rearrangement reaction of biarylphosphine-supported Pd(II) complexes was employed to synthesize 1,3,5-triaryl 2,4,6-triisopropylbenzene compounds, a class of molecules that has not previously been reported. The strain of the central hexasubstituted ring was investigated via X-ray crystallography.

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