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What makes a binding site a binding site?
Journal article   Peer reviewed

What makes a binding site a binding site?

Dagmar Ringe
Current opinion in structural biology, Vol.5(6), pp.825-829
1995
PMID: 8749372

Abstract

probe molecules hydrophobic binding sites proteins water
Organic probe molecules have recently been used to define hydrophobic binding sites on the surface of proteins. It appears that the presence of water on the surface of a protein plays a crucial role in the interaction between that protein and its binding site.

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